Key result
EECP fails to prompt early electrical remodeling or alter HR, PR, QRS, or QTc intervals.
Why the study?
Enhanced external counterpulsation therapy (EECP) improves coronary flow and ischemia time in severe CAD, but its effect on electrophysiologic remodeling is unknown.
Does enhanced external counterpulsation therapy (EECP) cause electrophysiologic remodeling in patients with severe coronary artery disease?
Population
28 patients with class II-III angina, imaging-proven ischemia, and severe, near-inoperable CAD
Comparison
Before and after EECP therapy
Design
Cohort study
Follow-up
7 weeks
Authors
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EECP improves angina without QTc or ECG changes in severe CAD; leaves open whether it avoids remodeling versus other hemodynamic therapies.
Cohort (n=28)
Does enhanced external counterpulsation therapy (EECP) cause electrophysiologic remodeling in patients with severe coronary artery disease?
p-value: p=NS
EECP provides significant clinical improvement in angina for patients with severe CAD without causing early electrical remodeling of the heart.
Henrikson et al. (2004) conducted a cohort in severe coronary artery disease (CAD) (n=28). Enhanced external counterpulsation therapy (EECP) was evaluated on Change in heart rate (HR), PR, QRS, or QTc intervals (p=NS). Enhanced external counterpulsation therapy did not prompt early electrical remodeling of the heart, with no significant changes in HR, PR, QRS, or QTc intervals (all P = NS).
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