Key result
Peak endocardial acceleration amplitude is highest in the RV at 1.32 g, reflecting global contractility.
Why the study?
It was not demonstrated in humans whether peak endocardial acceleration detected by a microaccelerometer sensor at different cardiac locations reflects local acceleration forces or whole heart contractility.
Comparison
PEA signals recorded at right ventricular apex, coronary sinus, right atrial appendage, and floating in right atrium
Design
Observational case series
Authors
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RV PEA may best reflect global contractility; hypothesis-generating for sensor-guided monitoring and requires prospective validation.
Observational (n=5)
Endocardial acceleration signals detected by a pacing lead sensor reflect global ventricular contractility rather than just local forces, suggesting potential utility for closed-loop pacing or hemodynamic monitoring.
Bongiorni et al. (1996) conducted an observational in Patients undergoing cardiac catheterization (n=5). BEST microaccelerometer sensor was evaluated on Peak endocardial acceleration (PEA) amplitude. Peak endocardial acceleration amplitude was highest in the right ventricle (1.32 g) and decreased in the right atrial appendage (0.75 g) and coronary sinus (0.45 g), reflecting global contractility.
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