Key result
Atypical porcine pestivirus detected in Chinese swine shares ~83% nucleotide identity with global strains.
Why the study?
Atypical porcine pestivirus (APPV) infection had not been previously reported in swine herds in China despite its detection in multiple other countries.
Observational
Yes
This study provides the first molecular evidence of atypical porcine pestivirus (APPV) infection in swine herds in China.
Answers are grounded in this paper and cite their sources.
Broadens APPV distribution to China; leaves open endemicity, transmission routes, and need for surveillance.
Atypical porcine pestivirus (APPV) have been detected in swine herds from the USA, Germany, the Netherlands, Spain and most recently in Austria, suggesting a wide geographic distribution of this novel virus. Here, for the first time, we reported APPV infection in swine herds in China. Newborn piglets from two separate swine herds in Guangdong province were found showing typical congenital tremors in July and August 2016. RT-PCR, sequencing and phylogenetic analysis showed APPV infection occurred. Phylogenetic analysis showed that Chinese APPV strains, GD1 and GD2, formed independent branch from the USA, Germany and the Netherlands. Nucleotide identities between members of the APPV ranged between 83.1% and 83.5%, and this showed APPV is highly diverse. It is apparent that this provides the first molecular evidence of APPV infection in swine herds in China.
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Zhang et al. (2017) conducted an observational in Atypical porcine pestivirus (APPV) infection. Atypical porcine pestivirus (APPV) infection was evaluated on Detection and phylogenetic analysis of APPV. Atypical porcine pestivirus (APPV) infection was identified for the first time in swine herds in China, with Chinese strains showing 83.1% to 83.5% nucleotide identity with other global strains.
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