Single-stage minimally invasive resection of synchronous left atrial myxoma and pulmonary atypical carcinoid: case report

Synchronous primary cardiac and pulmonary tumors are rare, presenting complex therapeutic challenges regarding surgical sequencing and perioperative risk. A 52-year-old man with atrial fibrillation was incidentally diagnosed with a left atrial myxoma and a suspicious left upper lobe hilar mass. Following multidisciplinary evaluation, a single-stage minimally invasive approach was performed. The procedure involved a right mini-thoracotomy for atrial myxoma resection under cardiopulmonary bypass, followed immediately by video-assisted thoracoscopic left upper lobectomy with systematic lymph node dissection. Pathology confirmed atrial myxoma and stage IB (pT2aN0M0) pulmonary atypical carcinoid. The postoperative course was uneventful; the patient remains disease-free at 36 months. In selected patients, simultaneous minimally invasive cardiothoracic resection is feasible and effective. This integrated strategy addresses competing risks-such as systemic embolization and oncologic progression-in a single setting, supporting a risk-adapted alternative to traditional staged approaches.