Key result
Meta-analysis abstract reports no quantitative findings for death and MI.
Why the study?
FFR-guided management of coronary stenosis requires adenosine, which is not licensed, unavailable, or expensive in some healthcare systems, limiting its use.
Meta-Analysis
No quantitative results reported in this Level 4 meta-analysis; leaves open the value of risk-assessment tools for clinical or research use.
In patients with coronary heart disease, revascularization can improve symptoms and in certain high-risk subgroups may improve prognosis. Coronary angiography provides anatomical information and the physiological significance of a stenosis can be determined using fractional flow reserve (FFR). Decisions on the need for and mode of revascularization can be optimized using FFR, however this involves administering adenosine to induce hyperemia. Generally, this test is well tolerated, but in some healthcare systems adenosine is either not licensed, unavailable, or expensive, limiting the use of FFR-guided management.
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Berry et al. (2017) conducted a meta-analysis in coronary heart disease. FFR-guided management was evaluated on Death and Myocardial Infarction. The provided abstract does not report any quantitative results or findings for the meta-analysis.
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