Key result
Combined leadless pacemaker and S-ICD proves safe and feasible in a hemodialysis patient.
Why the study?
Does combined implantation of an S-ICD and a helix-fixation leadless pacemaker provide safe and effective pacing and defibrillation without inappropriate shocks in a high-infection-risk dialysis patient?
Case Report (n=1)
No
Does combined implantation of an S-ICD and a helix-fixation leadless pacemaker provide safe and effective pacing and defibrillation without inappropriate shocks in a high-infection-risk dialysis patient?
Combined use of an S-ICD and a helix-fixation leadless pacemaker is a feasible, leadless alternative for patients requiring both defibrillation and pacing who are at high risk for transvenous lead infections, provided meticulous intraoperative screening for cross-sensing is performed.
May support leadless pacing plus S-ICD in high-infection-risk dialysis patients; leaves open confirmation in larger prospective studies.
Combined use of S‐ICD and LP provides an effective alternative for patients requiring defibrillation and pacing while avoiding transvenous leads. This strategy is particularly valuable for patients with a high risk of infection, though careful consideration must be given to minimizing potential device–device interactions.
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Zhou et al. (2026) conducted a case report in Ischemic cardiomyopathy, uremia on hemodialysis, sick sinus syndrome (n=1). Combined helix-fixation leadless pacemaker and subcutaneous implantable cardioverter-defibrillator was evaluated. Combined implantation of a helix-fixation leadless pacemaker and a subcutaneous implantable cardioverter-defibrillator was safe and feasible in a hemodialysis patient, with stable pacing parameters and no inappropriate shocks over a 1-year follow-up.
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