Key result
The first in-human report describes the combination of a leadless pacemaker and subcutaneous defibrillator for patients lacking vascular access for transvenous lead insertion.
Case Report
This first in-human report demonstrates the feasibility of combining a leadless pacemaker with a subcutaneous defibrillator for patients who need both pacing and ICD functions but lack vascular access for transvenous leads.
May offer pacing-defibrillation without vascular access; hypothesis-generating and should not yet change practice.
Although transvenous pacemakers and implantable cardioverter-defibrillators (ICD) have long been the standard of care, they are not without significant drawbacks. In recent years, major advances have been achieved in leadless pacemaker technology1 and entirely subcutaneous ICD (S-ICD) systems2 that obviate intracardiac leads and hence carry the potential to reduce associated complications. Unlike standard ICDs, the S-ICD is devoid of antibradycardia pacing capabilities. Nevertheless, certain patients, such as those lacking vascular access for transvenous lead insertion, may benefit from leadless devices with both pacing and ICD functions.
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Mondésert et al. (2015) conducted a case report in Patients requiring pacing and ICD functions lacking vascular access for transvenous lead insertion. Combination of a leadless pacemaker and subcutaneous defibrillator was evaluated. The first in-human report describes the combination of a leadless pacemaker and subcutaneous defibrillator for patients lacking vascular access for transvenous lead insertion.
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