Why the study?
Data concerning the treatment of pulmonary metastases from adrenal cortical carcinoma are sparse.
Does pulmonary resection improve survival in patients with pulmonary metastases from adrenal cortical carcinoma?
Population
24 patients with adrenal cortical carcinoma and pulmonary metastases
Comparison
Pulmonary resection vs chemotherapy or no therapy
Design
Retrospective cohort study
Follow-up
5 years
Key result
Pulmonary resection of metastases from adrenal cortical carcinoma was associated with a 71% 5-year survival, significantly longer than those not resected (0% survival at 3 years).
Authors
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May support resection in selected patients with resectable metastases; hypothesis-generating and requires prospective validation.
Cohort (n=24)
No
Does pulmonary resection improve survival in patients with pulmonary metastases from adrenal cortical carcinoma?
Absolute Event Rate: 71% vs 0%
Pulmonary resection of metastases from adrenal cortical carcinoma is associated with significantly prolonged survival compared to non-surgical management.
Kwauk et al. (1993) conducted a cohort in Adrenal cortical carcinoma with pulmonary metastases (n=24). Pulmonary resection vs. No resection (chemotherapy or no therapy) was evaluated on 5-year survival. Pulmonary resection of metastases from adrenal cortical carcinoma was associated with a 71% 5-year survival, significantly longer than those not resected (0% survival at 3 years).
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