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September 23, 2016Interactive Cardiovascular and Thoracic Surgery

The median overall survival was 18 months, and the 1-, 2- and 5-year survival rates were 66.5%, 40.5% and 28.2%, respectively, with significantly better prognosis for metachronous metastasis and negative lymph node status (P < 0.05).

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Why the study?

Does surgical treatment improve survival in patients with NSCLC and isolated adrenal metastasis?

Population

98 patients with Non-small-cell lung cancer and isolated adrenal metastatic lesions from 13 retrospective…

Design

Meta-analysis

Authors

XGXinliang GaoKZKewei ZhangMTMingbo Tang

Discussion

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Overview

Supports surgical consideration for selected NSCLC patients with isolated adrenal metastasis; extends evidence for metachronous and node-negative subgroups.

Structured PICO

Does surgical treatment improve survival in patients with NSCLC and isolated adrenal metastasis?

P
Population
98 patients with Non-small-cell lung cancer (NSCLC) and isolated adrenal metastatic lesions from 13 retrospective studies
I
Intervention
Surgical treatment (lobectomy or pneumonectomy and adrenalectomy)
O
Outcome
Overall survivalhard clinical

Surgical treatment for primary NSCLC and isolated adrenal metastasis provides a survival benefit, particularly in patients with metachronous metastasis or negative lymph node status.

Cite This Study

Gao et al. (2016) studied this question.

synapsesocial.com/papers/6a8aad8d0804b5b18767987chttps://doi.org/10.1093/icvts/ivw321
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Adrenalectomy For Isolated Metastasis In Five Patients With Lung Cancer: Single Centre Experience and Review of the Literature2011 · 2 citations
  2. 2Surgical management of adrenal metastases from lung cancer1998 · 76 citations
  3. 3Adrenal Oligometastases Secondary to Non-small Cell Lung Cancer—What is the Optimal Treatment Approach?2017 · 5 citations
  4. 4Adrenal Surgery for Synchronously Metastatic Adrenocortical Carcinoma: A Population‐Based Analysis2021 · 7 citations
  5. 5Adrenalectomy for Metastasis: The Impact of Primary Histology on Survival Outcome2024 · 2 citations