Key result
AF is linked to ~0.10 less MVA improvement after PBMV vs sinus rhythm.
Why the study?
The effects of percutaneous balloon mitral valvuloplasty in patients with mitral stenosis and atrial fibrillation compared to those with sinus rhythm were unclear.
Does percutaneous balloon mitral valvuloplasty result in different outcomes in patients with mitral stenosis and atrial fibrillation compared to those in sinus rhythm?
Population
6351 patients with mitral stenosis undergoing PBMV
Comparison
PBMV in patients with atrial fibrillation vs PBMV in patients with sinus rhythm
Authors
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AF predicts smaller MVA gains after PBMV; confirms reduced efficacy versus sinus rhythm and supports rhythm-stratified trials.
Meta-Analysis (n=6,351)
Does percutaneous balloon mitral valvuloplasty result in different outcomes in patients with mitral stenosis and atrial fibrillation compared to those in sinus rhythm?
Mean Difference: -0.1 (95% CI -0.14–-0.06)
Percutaneous balloon mitral valvuloplasty is less effective in improving mitral valve area and is associated with worse clinical outcomes in mitral stenosis patients with atrial fibrillation compared to those in sinus rhythm.
Liu et al. (2021) conducted a meta-analysis in Mitral stenosis (n=6,351). Atrial fibrillation vs. Sinus rhythm was evaluated on Changes in mitral valve area (MVA) (WMD -0.10, 95% CI -0.14, -0.06). Atrial fibrillation was associated with less favorable changes in mitral valve area (WMD -0.10; 95% CI -0.14, -0.06) compared to sinus rhythm after percutaneous balloon mitral valvuloplasty.
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