Key result
Whole nerve electrophysiology tracks diabetic symmetrical polyneuropathy progression but only assesses large myelinated axons.
Why the study?
Whole nerve electrophysiology provides objective measures sensitive to diabetic symmetrical polyneuropathy progression but indexes limited neural activity aspects and large myelinated axons only.
Does whole nerve electrophysiology accurately assess the progression of diabetic symmetrical polyneuropathy?
Population
Patients with diabetic symmetrical polyneuropathy
Design
Review
Authors
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Limits assessment of diabetic neuropathy progression to large myelinated fibers; leaves open need for small-fiber measures in future studies.
Does whole nerve electrophysiology accurately assess the progression of diabetic symmetrical polyneuropathy?
Whole nerve electrophysiology is a useful but limited tool for assessing diabetic neuropathy, primarily reflecting large myelinated axon function.
Joseph C. Arezzo (1997) conducted a review in Diabetic symmetrical polyneuropathy (DSPN). Whole nerve electrophysiology was evaluated. Whole nerve electrophysiology provides objective measures sensitive to diabetic symmetrical polyneuropathy progression, but is limited to indexing activity in large diameter, myelinated axons.
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