Key result
Peritoneal dialysis linked to better functional performance and fewer hospitalizations in refractory heart failure.
Why the study?
Randomized studies are lacking to establish the potential role of peritoneal dialysis in patients with congestive heart failure with or without end-stage renal disease.
Does peritoneal dialysis improve functional performance and reduce hospitalization in patients with congestive heart failure?
Does peritoneal dialysis improve functional performance and reduce hospitalization in patients with congestive heart failure?
Peritoneal dialysis may offer functional benefits and reduce hospitalizations in refractory heart failure, but robust randomized evidence is needed.
BACKGROUND: Peritoneal dialysis (PD) may be a useful technique in the treatment of patients with congestive heart failure, both with and without primary end-stage renal disease (ESRD). METHODS: In the treatment of patients with ESRD and congestive heart failure (CHF), PD has theoretical advantages compared with haemodialysis (HD), such as the absence of an arteriovenous fistula and the more gradual fluid removal. In cohort studies, the incidence of heart failure was less as compared with HD, however, randomized studies on this aspect are lacking. RESULTS: As an acute rescue treatment of patients with treatment refractory heart failure, functional improvement has been observed with the use of PD. However, fluid removal is less predictable compared with continuous haemofiltration therapies. CONCLUSIONS: As a long-term option for patients with treatment refractory CHF without ESRD, various case series showed improved functional performance and a reduction in hospitalization with the use of PD. However, also with the use of PD, median survival is still limited in these patients. Randomized studies are needed to establish the potential role of PD for this indication.
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Cnossen et al. (2006) conducted a review in Congestive heart failure with and without primary end-stage renal disease. Peritoneal dialysis vs. Haemodialysis and continuous haemofiltration therapies was evaluated. Peritoneal dialysis showed improved functional performance and reduced hospitalization in case series of refractory congestive heart failure, though randomized trials are lacking.
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