Key result
Polycystic ovary syndrome is not associated with overt metabolic syndrome despite frequent isolated features.
Why the study?
The frequency and characteristics of metabolic syndrome features in young women with PCOS compared to healthy controls were not well defined.
Comparison
PCOS women vs age-matched healthy females
Design
Case-control study
Authors
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Overt metabolic syndrome screening may have low yield in young PCOS patients; leaves open the relevance of isolated features.
Case-Control (n=142)
Absolute Event Rate: 1.6% vs 0%
Overt metabolic syndrome is rare in young Czech women with PCOS, although isolated metabolic risk factors such as low HDL cholesterol are common.
Vrbíková et al. (2005) conducted a case-control in Polycystic ovary syndrome (n=142). Polycystic ovary syndrome vs. Age-matched healthy females was evaluated on Overt metabolic syndrome (presence of three and more risk factors). Polycystic ovary syndrome was not associated with a higher prevalence of overt metabolic syndrome compared to healthy controls (1.6% vs 0%), though isolated features were frequent.
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