Key result
Low-dose landiolol infusion linked to sinus rhythm restoration in 89% of patients.
Why the study?
The efficacy of initiating landiolol hydrochloride at a low dose for postoperative supraventricular arrhythmia was investigated.
Does low-dose continuous intravenous infusion of landiolol hydrochloride improve heart rate and restore sinus rhythm in patients with postoperative supraventricular arrhythmia?
Population
38 patients with postoperative atrial flutter or fibrillation and 2 with paroxysmal atrial fibrillation
Comparison
Low-dose landiolol hydrochloride intravenous infusion
Design
Observational case series
Follow-up
2 hours
Authors
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May support landiolol for acute tachyarrhythmia control in select cases; leaves open confirmation in randomized trials.
Observational (n=38)
Does low-dose continuous intravenous infusion of landiolol hydrochloride improve heart rate and restore sinus rhythm in patients with postoperative supraventricular arrhythmia?
Low-dose continuous intravenous infusion of landiolol effectively reduces heart rate and restores sinus rhythm in patients with postoperative supraventricular arrhythmia.
Wariishi et al. (2009) conducted an observational in postoperative supraventricular arrhythmia (n=38). landiolol hydrochloride was evaluated on Return to sinus rhythm. Continuous intravenous infusion of low-dose landiolol restored sinus rhythm in 89% of patients and significantly reduced heart rate from 137 to 93 bpm (P<0.01).
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