Key result
Transcatheter VSD closure linked to occurrence and gradual worsening of AR 9-12 years post-procedure.
Why the study?
Long-term follow-up results after transcatheter ventricular septal defect closure were rare, despite known short- and mid-term safety and efficacy.
Does transcatheter closure of ventricular septal defect cause long-term aortic regurgitation?
Case Report
Does transcatheter closure of ventricular septal defect cause long-term aortic regurgitation?
Transcatheter closure of ventricular septal defects may be associated with late-onset, progressive aortic regurgitation 9-12 years after the procedure, highlighting the need for long-term surveillance.
May warrant extended AR surveillance after transcatheter VSD closure; leaves open incidence, mechanisms, and generalizability.
Ventricular septal defect is the most common type of CHD, and transcatheter ventricular septal defect closure has been shown to be an alternative to surgical closure with acceptable mortality and morbidity as well as encouraging results. Short-term and mid-term follow-ups have indicated the safety and efficacy of transcatheter closure, but long-term follow-up results were rare. In this report, we first found that aortic regurgitation occurred in patients 9-12 years following transcatheter closure and regurgitation were gradually increased. The findings indicate that the long-term outcome of transcatheter closure of ventricular septal defect may not be as satisfied as expected.
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Han et al. (2020) conducted a case report in Ventricular septal defect. Transcatheter ventricular septal defect closure was evaluated on Aortic regurgitation. Transcatheter closure of ventricular septal defect was associated with the occurrence and gradual increase of aortic regurgitation 9-12 years post-procedure.
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