Key result
Female sex shows no difference in post-CABG outcomes versus men after adjusting for height.
Why the study?
The impact of sex on outcomes after coronary artery bypass surgery remains controversial despite recent studies suggesting increased risk for women.
Does female sex increase operative risk after isolated coronary artery bypass surgery?
Comparison
Female sex vs male sex
Design
Cohort study with propensity score-based matching
Authors
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Shorter stature, not female sex, may drive CABG outcome differences; leaves open whether height-specific grafting improves results in observational cohorts.
Cohort (n=12,606)
No
Does female sex increase operative risk after isolated coronary artery bypass surgery?
Female sex per se does not increase operative risk in coronary artery bypass surgery; rather, shorter height (more common in women) affects outcomes, suggesting a potential benefit from sequential arterial grafting.
Ennker et al. (2009) conducted a cohort in Coronary artery disease requiring isolated coronary artery bypass surgery (n=12,606). Female sex vs. Male sex was evaluated on Operative mortality, arrhythmias, intensive care unit stay, and maximum creatine kinase-MB levels. After adjusting for preoperative characteristics including height, female sex was not associated with significant differences in clinical outcomes after coronary artery bypass surgery compared to men.
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