Key result
Cardiac movement alters LVM morphology but not the overall heart or pericardium.
Why the study?
Quantification of variations in the heart, pericardium, and left ventricular myocardium caused by cardiac movement during thoracic tumor radiotherapy was needed to inform protection strategies.
Observational (n=22)
The left ventricular myocardium exhibits significantly greater volumetric and morphological variations during the cardiac cycle compared to the whole heart and pericardium, suggesting a need for specific LVM protection during thoracic radiotherapy.
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May warrant accounting for cardiac motion in breath-hold radiotherapy planning; leaves open optimal margin strategies pending larger validation studies.
Tong et al. (2018) conducted an observational in Thoracic tumor radiotherapy (n=22). Cardiac movement was evaluated on Variations in the heart, pericardium, and left ventricular myocardium caused by cardiac movement. Morphological parameters between maximum and minimum DSC phases varied significantly for the left ventricular myocardium (p<0.05) but not for the heart or pericardium (p>0.05).
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