Key result
Preoperative oral nutritional supplements cut postoperative complications ~17% in colorectal cancer surgery.
Why the study?
The impact of preoperative oral nutritional supplements on postoperative clinical outcomes in colorectal cancer surgery patients remains controversial.
Do preoperative oral nutritional supplements reduce postoperative complications in colorectal cancer patients undergoing surgery?
Comparison
Preoperative oral nutritional supplements vs conventional or isoenergetic and isonitrogenous diet
Design
Systematic review and meta-analysis of randomized controlled trials
Authors
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Supports preoperative oral nutritional supplements in colorectal cancer surgery; strengthens Level 1 meta-analytic evidence for complication reduction.
Meta-Analysis (n=737)
Do preoperative oral nutritional supplements reduce postoperative complications in colorectal cancer patients undergoing surgery?
Relative Risk: 0.83 (95% CI 0.7–0.98)
p-value: p=0.03
Preoperative oral nutritional supplements may reduce the overall incidence of postoperative complications in patients undergoing colorectal cancer surgery.
Su et al. (2024) conducted a meta-analysis in Colorectal cancer (n=737). Preoperative oral nutritional supplements (ONS) vs. Conventional diet or an isoenergetic and isonitrogenous diet was evaluated on Total incidence of postoperative complications (RR 0.83, 95% CI 0.70-0.98, p=0.03). Preoperative oral nutritional supplements significantly reduced the total incidence of postoperative complications in patients undergoing colorectal cancer surgery (RR 0.83; 95% CI 0.70-0.98; P=0.03).
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