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June 18, 2026Journal of Parenteral and Enteral Nutrition

Perioperative nutrition therapy to optimize colorectal patient outcomes: A systematic review and meta‐analysis

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Authors

ATAlexander TroesterUniversity of MinnesotaSOShelbi OlsonUniversity of MinnesotaLWLindsay WeltonUniversity of Minnesota

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Implication

Systematic review evaluates perioperative nutritional interventions and their effects on colorectal outcomes, suggesting limited benefits.

Key Points

  • To evaluate the effectiveness of perioperative nutritional interventions on postoperative outcomes in colorectal surgery.
  • Conducted systematic review and meta-analysis of studies from 2000-2023.
  • Assessed interventions including protein supplementation, immunonutrition, carbohydrate loading, and postoperative diet progression.
  • Evaluated risk of bias and overall strength of evidence using standardized methods.
  • Twenty-seven studies included; ten showed low/moderate risk of bias.
  • Protein supplementation and immunonutrition may reduce surgical site infection rates compared to dietary advice alone; carbohydrate loading showed no significant difference.
  • Immunonutrition and carbohydrate loading likely do not affect length of stay and anastomotic leak rates.

Cite This Study

Troester et al. (2026) studied this question.

synapsesocial.com/papers/6a338de8630953a74978eb8ahttps://doi.org/10.1002/jpen.70112
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Also Consider

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  5. 5ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions2016 · 20,376 citations