Key result
Bone metastases occur in ~9% of soft tissue sarcoma patients, peaking in specific high-risk subtypes.
Why the study?
The incidence, distribution, timing, and radiologic characteristics of bone metastases from soft tissue sarcomas were not well characterized.
Population
320 patients with soft tissue sarcomas, exclusive of lymphomas
Design
Observational cohort study
Follow-up
Up to 66 months (mean 21.3 months)
Authors
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Prolonged bone surveillance may warrant consideration in soft tissue sarcoma; leaves open optimal subtype-specific protocols.
Observational (n=320)
Bone metastases occur in approximately 9.4% of patients with soft tissue sarcomas, predominantly presenting as osteolytic changes in regional or axial bones, with higher incidence in specific histologic subtypes.
Yoshikawa et al. (1999) conducted an observational in Soft tissue sarcomas (n=320). Soft tissue sarcomas was evaluated on Incidence of bone metastases. Bone metastases occurred in 9.4% of patients with soft tissue sarcomas, with higher incidences observed in alveolar soft part sarcoma, dedifferentiated liposarcoma, angiosarcoma, and rhabdomyosarcoma.
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