Why the study?
The cardiovascular and pulmonary sequelae in children recovering from multisystem inflammatory syndrome after SARS-CoV-2 infection remain incompletely characterized.
Observational (n=5)
Previously healthy children recovering from MIS-C may exhibit impaired myocardial blood flow, endothelial dysfunction, and reduced cardiopulmonary capacity, warranting further investigation.
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May warrant monitoring in post-MIS-C children; hypothesis-generating and leaves open prevalence plus long-term significance.
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Astley et al. (2022) conducted an observational in Multisystem inflammatory syndrome after SARS-CoV-2 infection (MIS-C) (n=5). Multisystem inflammatory syndrome after SARS-CoV-2 infection (MIS-C) was evaluated on Cardiovascular and pulmonary assessments including PET-CT myocardial blood flow, brachial flow-mediated dilation, and cardiopulmonary exercise test.
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