Key result
Echocardiography in dilated cardiomyopathy reveals frequent mild LV dilation and an average LVEF of ~40%.
Why the study?
Dilated cardiomyopathy is the most common cardiomyopathy phenotype but is often underdiagnosed with limited data available in the study setting.
Cross-Sectional (n=65)
No
In a tertiary care hospital setting, dilated cardiomyopathy commonly presents with congestive heart failure and reduced ejection fraction, highlighting the importance of routine echocardiography for diagnosis.
Descriptive findings in this small cross-sectional DCM cohort are hypothesis-generating; larger prospective studies needed before clinical application.
INTRODUCTION: Cardiomyopathies are diseases of heart muscle that may originate from genetic defects, cardiac myocyte injury or infiltration of myocardial tissues. Dilated cardiomyopathy is the most common phenotype and is often a final common pathway of numerous cardiac insults. Mostly it remains unknown in the absence of echocardiography, histopathology and genetic evaluation. Though common it is underdiagnosed with not much of data available in our setup. METHODS: This study was analytical cross-sectional study of hospital data on Echocardiographic findings in 65 patients of DCM visiting cardiology unit for Echocardiographic evaluation from 1st of February to 31st July 2018 for the period of six months in Shree Birendra Hospital, a tertiary care military hospital at Chhauni, Kathmandu. Pediatric age group patients and those who refused to give consent were excluded. Data obtained were entered in Microsoft Excel 2010 and analyzed by IBM SPSS 21. RESULTS: Among 65 patients enrolled 40 (61%) were male and 25 (39%) female with male to female ratio of 1.6:1. Elderly people (61-75 years) with an average age of 65 were commonly involved and they presented mostly with congestive heart failure, 32 (49%). Echocardiographic evaluation showed 36 (55%) with mildly dilated Left Ventricle (5.6-6.0cm). Majority had reduced Left ventricular systolic function with an average Ejection fraction (EF) of 39.6%. No significant difference between male and female with the average EF% (P=0.990) and there was no significant relation between age and average EF% (P=0.091). CONCLUSIONS: Dilated Cardiomyopathy is the commonest cardiomyopathy phenotype mostly presenting with congestive heart failure. It is often underdiagnosed in our part of the world, however echocardiography will easily detect the condition.
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Thapa et al. (2019) conducted a cross-sectional in Dilated Cardiomyopathy (n=65). Dilated cardiomyopathy was evaluated on Average Ejection Fraction. Echocardiographic evaluation of 65 patients with dilated cardiomyopathy revealed that 55% had a mildly dilated left ventricle and the average ejection fraction was 39.6%.
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