Key result
New arterial applanation tonometer demonstrates highly linear pressure and volume calibrations consistent with invasive measurements.
Why the study?
Traditional arterial tonometry permits noninvasive continuous recording of arterial pressure waveform but does not simultaneously register arterial volume changes.
Does the developed arterial applanation tonometer accurately measure arterial blood pressure and volume compared to invasive methods?
Does the developed arterial applanation tonometer accurately measure arterial blood pressure and volume compared to invasive methods?
The newly developed arterial applanation tonometer can reliably determine arterial blood pressure waveforms and volume changes, enabling noninvasive assessment of arterial wall compliance.
May enable simultaneous arterial pressure-volume recording; leaves open clinical validation before practice adoption.
Traditional arterial tonometry permits noninvasive and continuous recording of the arterial pressure waveform, by applanating a superficial artery supported by a bone. In the paper, we present an arterial tonometer to simultaneously register the blood pressure waveform and the arterial time-varying volume. The tonometer consisted mainly of a chamber filled with a conductive fluid, a flexible diphragm in touch with an artery, and a pressure sensor used to detect the underlying arterial pressure. In addition, four electrodes were in parallel diposed in the chamber, two of them were triggered with a constant-current source, and the voltage difference between the other two inner electrodes was assocated with the amount of change in the arterial volume. The pressure calibration curve performed with a mercury sphygmomanometer showed a fairly linear relationship (r = 0.998) between the tonometer's chamber pressure and the voltage output of the pressure-sensing circuit. The volume calibration was carried out with vessel-like cylinders of various diameters and a linear relationship (r = 0.884) of the change in vessel volume to the voltage output of the volume-sensing circuit was obtained. Clinical testing results revealed that the noninvasive blood pressure measurement with the tonometer was appreciably consistent with the invasive measurement with the catheter-tipped pressure transducer. In summary, the arterial applanation tonometer developed may be used to reliably determine the full arterial blood pressure waveform and the change in the arterial volume, and to make the wall compliance assessment of a superficial artery possible.
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Wang et al. (2004) studied this question. Arterial applanation tonometer vs. Catheter-tipped pressure transducer was evaluated on Pressure and volume calibration linearity and consistency with invasive measurement (r = 0.998 for pressure, r = 0.884 for volume). A newly developed arterial applanation tonometer demonstrated highly linear pressure (r=0.998) and volume (r=0.884) calibrations and was consistent with invasive catheter measurements.
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