Key result
Pharmacist-led education increases 3-month therapeutic goal attainment by ~85% vs control.
Why the study?
Most studies evaluating clinical pharmacy impact have focused on patient adherence or satisfaction, with limited data on direct clinical outcomes in chronic disease patients.
Does a pharmacist-led educational intervention improve therapeutic goal attainment in patients with hypertension, type 2 diabetes, or hypercholesterolaemia?
RCT (n=89)
Physician-blinded
Randomized
No
Does a pharmacist-led educational intervention improve therapeutic goal attainment in patients with hypertension, type 2 diabetes, or hypercholesterolaemia?
Absolute Event Rate: 61.7% vs 33.3%
p-value: p=0.015
A single pharmacist-led educational intervention significantly increases the proportion of patients with chronic cardiometabolic diseases reaching their therapeutic goals at 3 months.
Supports pharmacist-led education in cardiometabolic care; extends RCT evidence for multidisciplinary goal attainment strategies.
OBJECTIVES: In recent years, hospital pharmacists have gained more importance in the clinical support of patients. However, most of the studies evaluating the impact of clinical pharmacy have only studied patients' adherence or satisfaction. The aim of this study was to evaluate the direct clinical outcomes of a pharmacist-led educational intervention in patients with chronic disease. METHODS: We conducted a randomised, controlled, parallel, physician-blinded study in a day hospital and a consultation unit of a French teaching hospital over a 1-year period. Patients with hypertension, type 2 diabetes or hypercholesterolaemia who did not reach their therapeutic goals despite drug therapy were eligible. Patients in the intervention group received an intervention from a hospital pharmacist who provided patient education on pathology and drug management. The primary outcome was the proportion of patients reaching their therapeutic goals for blood pressure, glycated haemoglobin level or low-density lipoprotein cholesterol level at the 3-month follow-up consultation. RESULTS: From January to December 2015, 89 patients were included and 73 completed the study. In the intervention group, 61.7% (21/34) of the patients reached their therapeutic goals compared with 33.3% (13/39) in the control group (p=0.015). The intervention was significantly more effective in polypharmacy patients (60.0% (12/20) vs 16.7% (4/24); p=0.005), in those aged >60 years (57.9% (11/19) vs 26.1% (6/23); p=0.037) and in patients with a high education level (68.8% (11/16) vs 29.4% (5/17); p=0.024). CONCLUSION: A single pharmacist-led educational intervention has a clinical impact, doubling the proportion of patients reaching their therapeutic goals at 3 months, especially in polypharmacy patients and those aged >60 years. This study confirms the value of clinical involvement of hospital pharmacists in patient care in a consultation unit and day hospital.
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Delage et al. (2021) conducted an RCT in Hypertension, type 2 diabetes, and hypercholesterolaemia (n=89). Pharmacist-led educational intervention vs. Control group was evaluated on Proportion of patients reaching their therapeutic goals for blood pressure, glycated haemoglobin level or low-density lipoprotein cholesterol level at the 3-month follow-up consultation (p=0.015). A pharmacist-led educational intervention significantly increased the proportion of patients reaching therapeutic goals at 3 months compared to control (61.7% vs 33.3%, p=0.015).