Preparation of 1,3,4,‐Oxadiazol‐2‐carboxylic Acid Derivatives The synthesis of 5‐substituted‐1,2,4‐oxadiazol‐2‐carboxylic acid derivatives 3a‐g and 4a‐g by cyclodehydratation of diacylhydrazines 1a‐g and 2a‐g are described. Further derivatives 6 to 9 are obtained from 1,3,4‐oxadiazol‐2‐carboxethyl esters 3.
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Dost et al. (1985) studied this question.