Key result
Semi-automatic carotid wall segmentation maintains <1.5 mm² variability at adequate signal difference-to-noise ratios.
Why the study?
The impact of black blood MRI image quality and spatial resolution on the precision of vessel wall segmentation was unclear.
Comparison
Black blood MRI at seven different fields of view to vary spatial resolution
Design
Imaging study with repeated computer-assisted segmentation by two operators
Authors
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Higher-resolution black-blood carotid MRI preserves wall-area precision above SDNR 3; leaves open optimal protocols for plaque quantification in patients.
Semi-automatic segmentation of carotid artery wall boundaries using black blood MRI is robust for SDNR >3, allowing for higher spatial resolution despite reduced SNR.
Thomas et al. (2001) studied Healthy (n=4). Black blood MRI at different fields of view (FOVs) was evaluated on Variability of wall area measurements. Semi-automatic segmentation of carotid artery wall boundaries was robust for signal difference-to-noise ratio >3, with measurement variability <1.5 mm² for spatial resolutions of 0.22-0.37 mm.
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