Key result
BMI >25 linked to higher postoperative mortality vs BMI 18-25 in concurrent CABG and valve replacement.
Why the study?
The relationship between body mass index and postoperative mortality in patients undergoing CABG surgery plus valve replacement is uncertain.
Is a body mass index > 25 kg/m2 associated with higher postoperative mortality compared to a BMI of 18-25 kg/m2 in patients undergoing simultaneous CABG and valve replacement?
Cohort (n=202)
No
Is a body mass index > 25 kg/m2 associated with higher postoperative mortality compared to a BMI of 18-25 kg/m2 in patients undergoing simultaneous CABG and valve replacement?
In patients undergoing simultaneous CABG and valve replacement, a BMI > 25 kg/m2 is associated with higher postoperative mortality compared to a normal BMI (18-25 kg/m2).
Elevated BMI signals higher mortality risk after combined CABG-valve surgery; hypothesis-generating and should not yet change practice.
Background The relationship between body mass index (BMI) and postoperative mortality in patients who undergo coronary artery bypass graft (CABG) surgery plus valve replacement is uncertain. We aimed to investigate the association between body mass index (BMI) and postoperative mortality among patients who simultaneously underwent both CABG surgery plus valve replacement. Methods We retrospectively analyzed 1976 patients who underwent CABG surgery at our hospital between January 2017 and April 2021, including 202 patients who underwent valve replacement surgery during the same period. We analyzed the relationship between BMI and postoperative mortality. The relationship between BMI and postoperative mortality was assessed using smooth curve fitting and a Multiple logistic regression model. Results The results of smoothing curve fitting showed that BMI and postoperative mortality had a non-linear relationship, and the resulting curve exhibited a two-stage change and a breakpoint. Postoperative mortality is higher in patients that have a body mass index above 25 kg/m2compared to patients having a body mass index between 18 and 25 kg/m2. Conclusions Our study found a non-linear relationship between BMI and postoperative mortality in patients undergoing CABG plus valve replacement after adjusting for potential confounders. The causal relationship between BMI and postoperative mortality still requires further investigations.
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Dai et al. (2022) conducted a cohort in Coronary artery bypass graft surgery plus valve replacement (n=202). Body mass index >25 kg/m2 vs. Body mass index between 18 and 25 kg/m2 was evaluated on Postoperative mortality. Body mass index >25 kg/m2 was associated with higher postoperative mortality compared to a BMI of 18-25 kg/m2 in patients undergoing concurrent CABG and valve replacement.
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