Angiofibroma of soft tissue in the subcutis: A radiologic-pathologic study of three cases

Introduction: Angiofibroma of soft tissue (AFST) in the subcutis is a rare condition with few cases reported in the literature. Case Series: Three cases of angiofibroma of soft tissue in the subcutis of extremities are presented. Two cases which received surgery have no recurrent tumor for three years and one year, respectively. The remaining case underwent only excisional biopsy and was lost to follow-up. Conclusion: Radiological features of AFST were commonly well-circumscribed, round or oval configuration with homogeneous intermediate signal intensity on T1-weighted image on magnetic resonance imaging (MRI). The tumors were located in the subcutis of extremities and attached to the fascia or aponeurosis, but histologically no evidence of infiltration. The histopathological features were composed of oval or spindle cells with various degree of the cellularity, small vessels, and collagen fibers or myxoid matrix.