Key result
Diabetes impairs vascular function via oxidative stress, pointing to targeted biomarkers and therapies to reduce atherogenesis.
Why the study?
Diabetes mellitus impairs endothelial function and promotes pro-atherogenetic alterations through reduced nitric oxide bioavailability and increased oxidative stress, with unclear therapeutic implications.
Population
Patients with diabetes mellitus
Comparison
Various therapeutic strategies including insulin analogues, antihypertensive agents, statins, hypoglycemic agents, and antioxidant therapy
Design
Review
Authors
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Diabetes mellitus impairs vascular function through endothelial dysfunction and oxidative stress, which may be targeted by various therapeutic strategies and monitored via specific biomarkers.
Diabetes mellitus impairs vascular function through endothelial dysfunction and oxidative stress, which may be targeted by various therapeutic strategies and monitored via specific biomarkers.
Tousoulis et al. (2013) conducted a review in Diabetes Mellitus. Diabetes mellitus impairs vascular function through endothelial dysfunction and oxidative stress, highlighting the potential utility of specific biomarkers and therapies to mitigate atherogenesis.
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