Key result
Induced PACs post-cardioversion match spontaneous PAC locations in ~97% of cases, guiding AF ablation.
Why the study?
The low frequency of spontaneous PACs limits mapping and ablation of AF, and it is unclear if induced PACs after cardioversion originate from the same sites as spontaneous PACs.
Does mapping of induced PACs following cardioversion correlate with spontaneous PAC locations to guide ablation in patients with atrial fibrillation?
Comparison
Mapping of spontaneous PACs vs PACs induced following cardioversion of AF
Design
Observational study using EnSite 3000 noncontact mapping system
Follow-up
Mean 19±4 weeks
Authors
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May support induced PAC mapping to guide AF ablation; leaves open randomized confirmation before practice change.
Observational (n=12)
Does mapping of induced PACs following cardioversion correlate with spontaneous PAC locations to guide ablation in patients with atrial fibrillation?
p-value: p=0.5
Induced PACs following cardioversion highly correlate with spontaneous PAC locations, providing a reliable electrophysiologic parameter to guide AF ablation.
Sra et al. (2001) conducted an observational in Atrial fibrillation with spontaneous premature atrial contractions (n=12). Cardioversion to induce premature atrial contractions vs. Spontaneous premature atrial contractions was evaluated on Location similarity between spontaneous and induced premature atrial contractions (p=0.5). Induced premature atrial contractions following cardioversion originated from the same locations as spontaneous PACs in 97% of cases (P=0.5), providing a reproducible parameter for guiding AF ablation.
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