Why the study?
It was unclear whether pulmonary veins are the most common source of AF-initiating PACs simply because PACs arise there frequently or because PV PACs are intrinsically more arrhythmogenic.
Are premature atrial contractions arising from the pulmonary veins more likely to induce atrial fibrillation compared to other atrial sites in patients undergoing PVI ablation?
Population
100 patients undergoing PVI ablation
Comparison
PACs delivered from PV sites vs non-PV sites
Design
Prospective substudy of a randomized double-blind trial
Authors
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PV-origin PACs may preferentially induce AF; leaves open whether site-specific eradication prevents clinical events.
Are premature atrial contractions arising from the pulmonary veins more likely to induce atrial fibrillation compared to other atrial sites in patients undergoing PVI ablation?
This study protocol aims to determine if premature atrial contractions originating from the pulmonary veins are inherently more arrhythmogenic than those from other sites.
Howell et al. (2023) studied this question.
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