Key result
3.0-T high-resolution MRI demonstrates high reproducibility for assessing aortic PWV and compliance metrics.
Why the study?
The feasibility of a one-stop examination of aortic PWV, aortic distensibility, and brachial artery FMD using 3.0-T high-resolution MRI in healthy volunteers was not established.
Population
32 healthy volunteers aged 24-37 years
Comparison
Repeated measurements of aortic PWV, AD, and brachial artery FMD
Design
Observational study using 3.0-T high-resolution MRI
Follow-up
1 to 2 hours interval between repeated scans
Authors
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Supports integrated vascular MRI phenotyping in research; leaves open clinical adoption pending outcome validation.
Observational (n=32)
Effect estimate: ICC 0.95 (95% CI -0.55 to 0.50)
p-value: p=< 0.01
Comprehensive assessment of aortic compliance and brachial endothelial function can be achieved in a single examination using 3.0-T high-resolution MRI with good reproducibility.
Shan et al. (2012) conducted an observational in Healthy (n=32). 3.0-T high-resolution MRI vs. Repeated scan was evaluated on Reproducibility of aortic pulse wave velocity (PWV) (ICC 0.95, 95% CI -0.55 to 0.50, p=< 0.01). 3.0-T high-resolution MRI demonstrated high reproducibility for assessing aortic pulse wave velocity (ICC 0.95; P<0.01) and other compliance metrics in a single examination.
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