Key result
Atrial pacing-induced tachycardia decreases ventricular volumes in normal subjects without changing EF or CO.
Why the study?
The study aimed to characterize left ventricular function changes during atrial pacing-induced tachycardia in normal subjects.
Does atrial pacing alter left ventricular function and volumes in normal subjects?
Does atrial pacing alter left ventricular function and volumes in normal subjects?
Answers are grounded in this paper and cite their sources.
In normal subjects, tachycardia induced by atrial pacing decreases ventricular volumes without changing ejection fraction or cardiac output.
Multigated radionuclide angiography was performed at rest and during atrial pacing in 10 normal subjects. Left ventricular volumes in diastole and systole were measured by total counts in the region of interest of the left ventricle. Stroke volume, cardiac output, ejection fraction, and rates of ejection for each heart rate were calculated. As heart rate increased, there was a gradual decrease in end-diastolic, end-systolic, and stroke volumes without a significant change in cardiac output and ejection fraction. Ejection fraction rate increased and the uncorrected ejection rate decreased with the increase in heart rate. The normal response to tachycardia induced by atrial pacing was a decrease in ventricular volumes without a change in ejection fraction or cardiac output.
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Rozenman et al. (1984) studied Normal subjects (n=10). Atrial pacing vs. Rest was evaluated on Left ventricular volumes, stroke volume, cardiac output, and ejection fraction. Atrial pacing-induced tachycardia in normal subjects decreased ventricular volumes without changing ejection fraction or cardiac output.
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