Surgical Management of Giant Abdominal Liposarcoma Two Case Reports

Introduction: Abdominal sarcomas, accounting for 15–20% of all sarcomas, are rare and often grow large before causing symptoms, leading to limited reports on the disease. Case presentation: This review discusses two surgical cases: a 13.5 kg retroperitoneal liposarcoma (40 cm) in a 71-year-old male and a 6 kg liposarcoma in the small bowel mesentery in a 46-year-old female. Both patients presented with large abdominal tumors causing compressive symptoms. Contrastenhanced CT scans suggested liposarcoma, and both underwent complete surgical excisions without complications. They were discharged after 7 days, with final diagnoses confirming retroperitoneal liposarcoma. Postoperative management involved active surveillance without chemotherapy or radiotherapy. After 1 year, no recurrence or metastasis has been observed. Conclusions: Abdominal liposarcoma often presents as locally advanced at the time of diagnosis, often due to the absence of noticeable symptoms. Currently, chemotherapy for retroperitoneal soft-tissue sarcomas is not effective, and radiotherapy has limited efficacy due to the toxicity affecting adjacent intra-abdominal structures. The exclusive treatment option is a complete surgical excision to achieve successful outcomes. In these two cases, we performed complete resections without combined resection of the surrounding organ. Furthermore, we will continue to observe our patients closely for recurrence.