Key result
En bloc excision of giant retroperitoneal liposarcoma precedes fatal tumor relapse at 9 months.
Why the study?
Liposarcomas are notable for their frequently large size, but clinical outcomes after excision of extremely large dedifferentiated liposarcomas are not well documented.
Giant retroperitoneal dedifferentiated liposarcomas can relapse and be fatal despite en bloc excision.
Even complete resection may fail to prevent early relapse and death; leaves open the value of multimodal approaches.
Liposarcomas are one of the most common soft tissue sarcomas of adulthood. Liposarcomas are remarkable because of their frequently large size. We report a case with an extremely large dedifferentiated liposarcoma that weighed 18 kg. Although it was capsulated and could be excised en bloc, the patient suffered a relapse 9 months later and died 1 year after the operation.
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Inoue et al. (2005) studied this question. En bloc excision of an 18-kg giant retroperitoneal dedifferentiated liposarcoma was followed by tumor relapse at 9 months and patient death 1 year post-operation.
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