Key result
RT-PCR after BHK-21 cell adaptation detects FMDV serotype A in ~13% of suspected animal samples.
Why the study?
A sensitive, reliable, and rapid diagnosis method is crucial for effective control of Foot and Mouth Disease in Bangladesh due to its devastating economic consequences.
Observational (n=23)
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Direct FMDV detection without BHK-21 adaptation remains challenging; leaves open optimized RT-PCR protocols for endemic settings.
Quddus et al. (2016) conducted an observational in Foot and Mouth Disease (n=23). RT-PCR and BHK-21 cell adaptation was evaluated on Detection of FMDV serotype A. RT-PCR following BHK-21 cell adaptation detected FMDV serotype A in 13.04% (3 of 23) of tissue samples from suspected animals in Bangladesh.
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