Key result
Sevoflurane vital capacity induction speeds loss of consciousness versus IV propofol with similar side effects.
Why the study?
The comparative efficacy and side effect profiles of vital capacity inhaled induction with sevoflurane versus intravenous propofol induction for adult ambulatory anesthesia were not well established.
Does vital capacity inhaled induction with sevoflurane reduce time to loss of consciousness compared to IV induction with propofol in adult ambulatory surgical patients?
Comparison
Vital capacity inhaled induction with sevoflurane vs intravenous induction with propofol
Design
Randomized controlled trial
Follow-up
Until discharge
Authors
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VC sevoflurane induction may speed loss of consciousness versus propofol in ambulatory cases; leaves open routine preference pending confirmatory trials.
RCT (n=56)
Does vital capacity inhaled induction with sevoflurane reduce time to loss of consciousness compared to IV induction with propofol in adult ambulatory surgical patients?
Vital capacity induction with sevoflurane produces a faster loss of consciousness with similar recovery times and patient satisfaction compared to propofol induction in adults undergoing ambulatory surgery.
Philip et al. (1999) conducted an RCT in Adult ambulatory anesthesia (n=56). Vital capacity inhaled induction with sevoflurane vs. Propofol 2-mg/kg bolus IV was evaluated on Times to loss of consciousness and induction side effects. Vital capacity induction with sevoflurane produced a significantly faster loss of consciousness compared to propofol IV induction, with similar side effects and recovery times.
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