Key result
Partial excision and radiation successfully treat rare brown fat liposarcoma without recurrence in Turner's syndrome.
Why the study?
The significance of circulating fibrin degradation products (F.D.P.) levels and their relation to in-vivo coagulation and fibrinolysis dynamics in healthy subjects was unclear.
Do exercise and intravenous adrenaline affect fibrin degradation product levels in healthy subjects?
Population
106 apparently healthy subjects
Comparison
Exercise and intravenous adrenaline vs resting state
Design
Cross-sectional study with immunoassay measurements
Authors
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Weak FDP-plasminogen activator correlation indicates complex fibrin dynamics; leaves open whether resting levels prove continuous turnover in normals.
Case Report (n=1)
Do exercise and intravenous adrenaline affect fibrin degradation product levels in healthy subjects?
Fibrin degradation products are detectable in almost all healthy subjects at rest, suggesting a continuous dynamic equilibrium between coagulation and fibrinolysis.
Lowry et al. (1967) conducted a case report in Malignant tumor of brown fat (liposarcoma) and Turner's syndrome (n=1). Partial surgical excision and megavoltage irradiation was evaluated on Tumor recurrence. A rare malignant tumor of brown fat (liposarcoma) was identified in a 24-year-old woman with Turner's syndrome and successfully treated with partial excision and radiation therapy without recurrence.
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