Key result
Echo and CMR successfully diagnose Loeffler endocarditis in a patient presenting with HFpEF.
Why the study?
Loeffler endocarditis is an uncommon cause of HFpEF with serious complications, requiring imaging for diagnosis and characterization.
Case Report (n=1)
Multimodality imaging, including echocardiography and cardiac MRI, is valuable for diagnosing rare causes of HFpEF such as Loeffler endocarditis.
Multimodality imaging may aid rare HFpEF diagnoses; case reports leave broader adoption open.
We report the case of a 69-year-old female patient in which echocardiography and cardiac magnetic resonance imaging were used to diagnose a patient presenting with heart failure with preserved ejection fraction (HFpEF) due to Loeffler endocarditis. Loeffler endocarditis is an uncommon cause of heart failure with preserved ejection fraction, triggered by eosinophil and lymphocyte infiltration of the endomyocardium, followed by the formation of thrombus in the afflicted area, and eventually fibrosis. This condition is due to an increased number of eosinophils associated with allergies, infections, systemic conditions, as well as malignancies and hypereosinophilic syndrome. Loeffler endocarditis can lead to serious complications, such as progressive heart failure, systemic thromboembolic events, or arrhythmias (including sudden cardiac death).
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Lupu et al. (2022) conducted a case report in Heart failure with preserved ejection fraction (HFpEF) due to Loeffler endocarditis (n=1). Echocardiography and cardiac magnetic resonance imaging was evaluated on Diagnosis of Loeffler endocarditis. Echocardiography and cardiac magnetic resonance imaging successfully diagnosed Loeffler endocarditis in a 69-year-old female presenting with heart failure with preserved ejection fraction.
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