Key result
Renal sympathetic denervation linked to sustained SBP reductions over ~5 years in treatment-resistant hypertension.
Why the study?
The long-term effects of renal sympathetic denervation on pharmacologically uncontrollable hypertension were not well documented beyond 1-2 years.
Does renal sympathetic denervation improve blood pressure control in patients with pharmacologically uncontrollable hypertension over long-term follow-up?
Observational (n=7)
No
Does renal sympathetic denervation improve blood pressure control in patients with pharmacologically uncontrollable hypertension over long-term follow-up?
Renal sympathetic denervation may provide sustained, long-term blood pressure reduction in patients with resistant hypertension.
May support durable BP reduction with renal denervation in resistant hypertension; leaves open confirmation in randomized trials.
The present paper is an extension to our earlier publication (Šochman et al. 2016) documenting a beneficial effect of renal sympathetic denervation on pharmacologically uncontrollable hypertension in a group of seven patients followed up for 1-2 years post-procedure. The same patients remained on ambulatory follow-up for another 5-6 years, with the beneficial effect persisting throughout the follow-up period while on the same medication.
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Peregrín et al. (2019) conducted an observational in Resistant arterial hypertension (n=7). Renal sympathetic denervation was evaluated on Systolic blood pressure reduction.
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