Key result
Intensity-modulated radiotherapy safely controls recurrent Kimura's disease without toxicity at 28 months.
Why the study?
Kimura's disease is a rare chronic inflammatory disorder with limited data on effective treatments for recurrent cases after surgery and medical therapy.
Does intensity-modulated radiotherapy improve local control and cosmetic outcomes in a patient with recurrent Kimura's disease?
Case Report (n=1)
Does intensity-modulated radiotherapy improve local control and cosmetic outcomes in a patient with recurrent Kimura's disease?
Intensity-modulated radiotherapy may be an effective and safe treatment modality for recurrent Kimura's disease.
IMRT may be considered for recurrent Kimura's disease; leaves open the need for prospective trials.
Kimura's disease (KD) is a rare, chronic inflammatory disorder of unknown aetiology, which commonly affects men of the Asian race. Here, we present a case capsule of a 39- year-old man with KD of the left cheek, managed initially by surgery alone. He developed local recurrence after 6 months and was treated with steroids and isotretinoin. Eventually, steroids were discontinued due to toxicity and the lesion progressively increased in size. The patient was successfully treated using intensity-modulated radiotherapy with simultaneous integrated boost as a primary modality with minimal adverse effects. The patient has good local control and cosmetic outcome with no radiation-related toxicity at a follow-up period of 28 months.
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Venkatasai et al. (2021) conducted a case report in Kimura's disease (n=1). Intensity-modulated radiotherapy with simultaneous integrated boost was evaluated on Local control, cosmetic outcome, and radiation-related toxicity. Intensity-modulated radiotherapy successfully treated recurrent Kimura's disease, yielding good local control and cosmetic outcome with no radiation-related toxicity at 28 months.
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