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May 18, 2010West African Journal of MedicineOpen Access

Colorectal Carcinoma An Update of Current Trends in Accra

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Authors

JDJonathan Cuthbert Dakubo

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Implication

Prospective study reveals rising colorectal cancer rates and late-stage presentation in an urban population, indicating an evolving disease burden alongside demographic aging.

Key Points

  • Provide an updated evaluation of colorectal cancer incidence, clinical presentations, and clinicopathological characteristics over a ten-year period.
  • Conducted a prospective study of N=359 confirmed colorectal cancer cases diagnosed between January 1997 and December 2007 in Accra, Ghana.
  • Assessed demographic variables, crude incidence rates, clinical presentations, tumor locations, Astler-Coller stages, histological grades, and surgical outcomes.
  • The crude incidence rate was 11.18 per 100,000 population overall (12.53 in males, 9.87 in females), with an annual incidence of 32.6 new cases.
  • Most frequent presentations were rectal bleeding (51.1%), abdominal mass (21.1%), and intestinal obstruction (17.3%), with tumors situated in the colon (53.2%) and rectum (46.8%).
  • Adenocarcinoma predominated in 89.4% of cases; tumors presented at advanced Astler-Coller stages C2 (36.7%) and C1 (22.1%), with 225 surgical resections performed and a 6.1% post-operative mortality rate.

Cite This Study

Jonathan Cuthbert Dakubo (2010) studied this question.

synapsesocial.com/papers/6ab0764d1fc40e6e43e9589dhttps://doi.org/10.55891/wajm.v29i3.6
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