Key result
Elevated triglycerides linked to ~81% higher odds of CKD in hypertensive patients.
Why the study?
Hypertension is a leading cause of chronic kidney disease, and the association between metabolic syndrome components and CKD prevalence in hypertensive patients is unclear.
Are metabolic syndrome components associated with a higher prevalence of chronic kidney disease in patients with hypertension?
Population
2484 patients with hypertension in 15 cities in China
Comparison
Presence vs absence of metabolic syndrome components and different hypertension grades
Design
Multi-center cross-sectional study
Authors
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May inform CKD risk stratification in hypertension; hypothesis-generating and requires longitudinal confirmation.
Cross-Sectional (n=2,484)
Yes
Are metabolic syndrome components associated with a higher prevalence of chronic kidney disease in patients with hypertension?
Odds Ratio: 1.81 (95% CI 1.28–2.57)
p-value: p=<0.01
In hypertensive patients, metabolic syndrome components, particularly elevated triglycerides, are strongly and independently associated with chronic kidney disease.
Xie et al. (2019) conducted a cross-sectional in Hypertension (n=2,484). Elevated triglycerides vs. Normal triglycerides was evaluated on Prevalence of chronic kidney disease (CKD) (OR 1.81, 95% CI 1.28-2.57, p=<0.01). Elevated triglycerides were significantly associated with the prevalence of chronic kidney disease in patients with hypertension (OR 1.81), independent of diabetes and hypertension grades.
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