Key result
Diabetes linked to ~40% higher rate of new-onset AF after off-pump CABG.
Why the study?
The effects of diabetes mellitus on intraoperative variables and postoperative complications in patients undergoing off-pump coronary artery bypass grafting were not well defined.
Does diabetes mellitus increase the risk of perioperative complications in patients undergoing off-pump coronary artery bypass grafting?
Cohort (n=2,108)
Does diabetes mellitus increase the risk of perioperative complications in patients undergoing off-pump coronary artery bypass grafting?
Answers are grounded in this paper and cite their sources.
Diabetes mellitus is a significant risk factor for prolonged ICU stay, new-onset atrial fibrillation, and postoperative infection in patients undergoing off-pump CABG.
Objective. To investigate the effects of diabetes mellitus (DM) in patients undergoing off-pump coronary artery bypass grafting (OPCAB).Method. A total of 728 patients with DM and 1380 patients without DM who underwent OPCAB treatment from March 2012 to April 2015 were reviewed. The effects of DM on intraoperative variables and postoperative complications were determined using propensity score analysis.Results. Two well-matched subgroups were selected using propensity score analysis (DM = 728, no-DM = 728) to compare the perioperative outcome. The duration of the ICU stay, in hours (55.2 ± 53.0 versus 49.29 ± 51.30, P<0.05 ), postoperative new-onset atrial fibrillation (20.9% versus 14.97%, P<0.05 ), and postoperative infection (9.2% versus 4.67%, P<0.05 ) were greater in DM patients, as indicated by univariate analysis.Conclusion. OPCAB was found to be effective in DM patients, but postoperative infection and postoperative new-onset atrial fibrillation were found to be more likely to occur in DM patients than in other patients. DM was found to be a powerful risk factor for postoperative infection and postoperative new-onset atrial fibrillation.
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Liu et al. (2016) conducted a cohort in Patients undergoing off-pump coronary artery bypass grafting (OPCAB) (n=2,108). Diabetes mellitus vs. No diabetes mellitus was evaluated on Postoperative new-onset atrial fibrillation (p=<0.05). Diabetes mellitus in patients undergoing off-pump coronary artery bypass grafting was associated with higher rates of postoperative new-onset atrial fibrillation.
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