Key result
Diabetes mellitus did not significantly affect long-term all-cause mortality (5.8% vs. 4.1%, P=0.216) but significantly increased the overall incidence of major adverse cardiovascular and cerebrovascular events in patients with ischemic heart failure undergoing CABG.
Why the study?
Few studies have examined the impact of diabetes mellitus on long-term outcomes after surgical revascularization in patients with ischemic heart failure, and existing results remain controversial.
Does diabetes mellitus increase the risk of long-term adverse outcomes in patients with ischemic heart failure undergoing CABG?
Population
Patients with ischemic heart failure who underwent CABG
Comparison
Patients with DM vs patients without DM
Design
Single-hospital propensity-matched study
Follow-up
Mean 73 months
Authors
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DM associated with higher long-term MACCE but not mortality after CABG in ischemic HF; leaves open whether targeted strategies improve outcomes.
Cohort (n=346)
No
Does diabetes mellitus increase the risk of long-term adverse outcomes in patients with ischemic heart failure undergoing CABG?
Absolute Event Rate: 5.8% vs 4.1%
p-value: p=0.216
In patients with ischemic heart failure undergoing CABG, diabetes mellitus is associated with a higher risk of long-term major adverse cardiovascular and cerebrovascular events, though it does not significantly impact all-cause mortality.
Liu et al. (2021) conducted a cohort in Ischemic heart failure (n=346). Diabetes mellitus vs. Non-diabetes mellitus was evaluated on All-cause death (p=0.216). Diabetes mellitus did not significantly affect long-term all-cause mortality (5.8% vs. 4.1%, P=0.216) but significantly increased the overall incidence of major adverse cardiovascular and cerebrovascular events in patients with ischemic heart failure undergoing CABG.
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