Key result
Orthotopic heart transplantation delivers excellent long-term outcomes with ~74% survival at ten years.
Why the study?
To improve long-term results of heart transplantation by analyzing causes of death relative to time after transplantation.
Cohort (n=201)
No
Adult orthotopic heart transplantation demonstrates excellent long-term survival up to 10 years, with late mortality driven primarily by non-cardiac causes such as infection and malignancy rather than allograft vasculopathy.
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Supports counseling on durable adult heart transplant survival; extends single-center data but leaves open multicenter validation and non-cardiac risk reduction.
Jung et al. (2011) conducted a cohort in End-stage heart failure (n=201). Orthotopic heart transplantation was evaluated on Overall survival rate at 10 years. Orthotopic heart transplantation in adults resulted in excellent long-term outcomes, with 1-, 5-, and 10-year survival rates of 95.5%, 86.9%, and 73.5%, respectively.
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