Key result
Isolated AVR carries ~6% in-hospital mortality, linked to advanced age, elevated liver enzymes, and reoperation.
Why the study?
Risk factors associated with in-hospital and late survival after isolated aortic valve replacement were not fully characterized.
What are the preoperative and operative risk factors associated with in-hospital mortality and late survival in patients undergoing isolated aortic valve replacement?
Population
190 patients undergoing isolated aortic valve replacement at Seoul National University Hospital in Korea
Comparison
Risk factors associated with outcomes after isolated aortic valve replacement
Design
Univariate analysis of a cohort study
Follow-up
Up to 7 postoperative years
Authors
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Informs preoperative counseling for isolated AVR; extends observational risk data but leaves practice change open pending prospective validation.
Cohort (n=190)
No
What are the preoperative and operative risk factors associated with in-hospital mortality and late survival in patients undergoing isolated aortic valve replacement?
Advanced age, NYHA class III/IV, preoperative hepatic dysfunction, and reoperation are significant risk factors for early and late mortality following isolated aortic valve replacement.
Sung et al. (1993) conducted a cohort in Isolated aortic valve replacement (n=190). Isolated aortic valve replacement was evaluated on In-hospital death. Isolated aortic valve replacement had a 5.8% in-hospital mortality rate, with advanced age, elevated liver enzymes, and reoperation identified as significant risk factors.
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