Key result
MetS in newly diagnosed OSAS is linked to ~25% lower serum vitamin D levels.
Why the study?
Obstructive sleep apnea syndrome (OSAS) has been associated with metabolic syndrome (MetS) and lowered vitamin D levels, but reports on vitamin D levels in OSAS patients with MetS are inconclusive.
Are serum vitamin D levels lower in OSAS patients with concurrent metabolic syndrome compared to those without?
Population
107 subjects (88 men) newly diagnosed with OSAS by polysomnography
Comparison
OSAS patients with MetS vs OSAS patients without MetS
Design
Cross-sectional study
Authors
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Does not support routine vitamin D screening in OSAS; hypothesis-generating for prospective trials on supplementation.
Cross-Sectional (n=107)
Are serum vitamin D levels lower in OSAS patients with concurrent metabolic syndrome compared to those without?
Absolute Event Rate: 18% vs 23.9%
p-value: p=0.012
In patients with newly diagnosed obstructive sleep apnea syndrome, the concurrent presence of metabolic syndrome is associated with significantly lower serum vitamin D levels and greater daytime sleepiness.
Archontogeorgis et al. (2018) conducted a cross-sectional in Obstructive Sleep Apnea Syndrome (n=107). Metabolic syndrome vs. No metabolic syndrome was evaluated on Serum 25-hydroxy vitamin D [25(OH)D] levels (p=0.012). Among newly diagnosed OSAS patients, concurrent metabolic syndrome was associated with significantly lower serum 25(OH)D levels compared to those without metabolic syndrome (18 vs 23.9 ng/mL, p=0.012).