Key result
Obstructive sleep apnea is linked to ~26% lower serum vitamin D levels versus controls.
Why the study?
Obstructive sleep apnoea syndrome has been associated with decreased vitamin D levels, but previous reports have been inconclusive.
Are serum 25-hydroxyvitamin D levels associated with the presence and severity of obstructive sleep apnoea syndrome?
Comparison
OSAS patients (AHI ≥5/h) vs non-apnoeic controls (AHI <5/h)
Design
Observational cross-sectional study
Authors
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Hypothesis-generating for vitamin D assessment in OSA; prospective trials needed before clinical adoption.
Observational (n=169)
Are serum 25-hydroxyvitamin D levels associated with the presence and severity of obstructive sleep apnoea syndrome?
Absolute Event Rate: 17.8% vs 23.9%
p-value: p=0.019
Vitamin D levels are significantly lower in patients with obstructive sleep apnoea syndrome and inversely correlate with disease severity.
Archontogeorgis et al. (2017) conducted an observational in Obstructive sleep apnoea syndrome (OSAS) (n=169). Obstructive sleep apnoea syndrome (OSAS) vs. Non-apnoeic controls (AHI <5/h) was evaluated on Serum 25-hydroxyvitamin D [25(OH)D] levels (p=0.019). Obstructive sleep apnoea syndrome was associated with significantly lower serum 25(OH)D levels compared to non-apnoeic controls (17.8 vs. 23.9 ng/ml; p=0.019).
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