Key result
Job stress domains are not associated with subclinical cardiovascular disease measured by CAC or CIMT.
Why the study?
The relationship between job stress and subclinical cardiovascular disease was evaluated to clarify potential associations.
Does job stress increase the risk of subclinical cardiovascular disease in the ELSA-Brasil cohort?
Observational
Does job stress increase the risk of subclinical cardiovascular disease in the ELSA-Brasil cohort?
Job stress domains do not appear to be independently associated with subclinical cardiovascular disease as measured by CAC or CIMT after adjusting for traditional risk factors.
No association after adjustment; leaves open any causal role of job stress in subclinical atherosclerosis and requires prospective study.
OBJECTIVE: We aimed to evaluate the relationship between job stress and subclinical cardiovascular disease at ELSA-Brasil. METHODS: We considered job stress domains (demand, skill discretion, decision authority, and social support) as independent variables and coronary artery calcium (CAC more than 0) and carotid intima-media thickness (CIMT more than P75% as a continuous variable) as dependent ones. Odds ratio (OR) and 95% confidence interval (95% CI) were presented crude, with further adjustments for sociodemographic, cardiovascular risk factors, and lifestyle variables. Linear regression models were built for CIMT using the same covariates. RESULTS: Although significant associations were observed in the crude models, after multivariate adjustment CAC and CIMT were not significantly associated with demand, skill discretion, decision authority, and social support. CONCLUSIONS: Our results did not support an association between job stress and subclinical cardiovascular disease measured by CAC or CIMT.
No takes yet. Share an insight, caveat, or question.
Lorentz et al. (2020) conducted an observational in Subclinical cardiovascular disease. Job stress was evaluated on Coronary artery calcium (CAC > 0) and carotid intima-media thickness (CIMT > P75%). Job stress domains were not significantly associated with subclinical cardiovascular disease measured by coronary artery calcium or carotid intima-media thickness after multivariate adjustment.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: